Human growth hormone therapy in Prader-Willi syndrome.
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چکیده
202 Isabella is a nine-year-old with Prader-Willi syndrome (PWS), secondary to a paternal interstitial deletion (15q-). Her parents seek your advice on the use of human growth hormone (GH) because despite a program of physical activity and rigorous dietary management with the red-yellow-green weight control system, their daughter’s obesity is increasing . Lately, she is more tired, has headaches and falls asleep during daytime. Although she was always short, they noticed that her growth is slowing down even further. An Internet search by the parents has suggested that children with PWS may benefit from GH therapy. Human growth hormone therapy in Prader-Willi syndrome
منابع مشابه
Growth Hormone Therapy in Adults with Prader-Willi Syndrome
Prader-Willi syndrome (PWS) is characterized by hyperphagia, obesity if food intake is not strictly controlled, abnormal body composition with decreased lean body mass and increased fat mass, decreased basal metabolic rate, short stature, low muscle tone, cognitive disability, and hypogonadism. In addition to improvements in linear growth, the benefits of growth hormone therapy on body composit...
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AIMS To evaluate the effect of the administration of growth hormone on stature, body weight, and body composition in children aged between 4 and 10 years with Prader-Willi syndrome. METHODS Height, weight, and skinfold thickness were recorded in 25 children using standard anthropometric techniques at recruitment, and six months later, shortly before the start of daily subcutaneous injections ...
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عنوان ژورنال:
- Paediatrics & child health
دوره 10 4 شماره
صفحات -
تاریخ انتشار 2005